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Cereal Foods World, Vol. 63, No. 5
DOI: https://doi.org/10.1094/CFW-63-5-0188
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High-Amylose Wheat Foods: A New Opportunity to Meet Dietary Fiber Targets for Health
M. Newberry,1,2 P. Berbezy,3,4 D. Belobrajdic,5,6 S. Chapron,3,7 P. Tabouillot,3,8 A. Regina,1,9 and A. Bird5,10

1 Commonwealth Scientific and Industrial Research Organisation, Agriculture and Food, GPO Box 1700, Canberra, ACT 2601, Australia.
2 E-mail: marcus.newberry@csiro.au
3 Limagrain Céréales Ingrédients, ZAC Les Portes de Riom, Ave George Gershwin, 63200 Riom Cedex, France.
4 Corresponding author. Tel: +33 (0)4 7367 1724; Fax: +33 (0)4 7367 1710; E-mail: pierre.berbezy@limagrain.com
5 Commonwealth Scientific and Industrial Research Organisation, Health and Biosecurity, PO Box 10041, Adelaide, SA 5000, Australia.
6 E-mail: damien.belobrajdic@csiro.au
7 E-mail: sophie.chapron@limagrain.com
8 E-mail: pascal.tabouillot@limagrain.com
9 E-mail: ahmed.regina@csiro.au
10 E-mail: tony.bird@csiro.au


Abstract

Poor diet is recognized as a major risk factor that can be modified to prevent the growing prevalence of noncommunicable diseases globally and the deaths attributed to them. Enhancing the nutritional quality of staple foods such as cereals offers a promising strategy for addressing poor diets. Whole grain wheat is of particular importance in this strategy because of its well-established health-promoting potential and its versatility as an ingredient, which can be used to produce foods that appeal to consumers. With this in mind we utilized wheat breeding strategies to develop a wheat with a high amylose content (>80%) in the starchy endosperm and have shown that this improves indices of glycemic and digestive health. Testing revealed the high amylose content resulted in significantly more resistant starch (RS) in breads and popped wheat (>200% more RS), udon noodles (60-fold more RS), and ramen noodles (15-fold more RS) than was found in equivalent products made using conventional wheats. These increases in RS were obtained using refined (white) high-amylose wheat (HAW) flour, which did not compromise processing, end-product quality, or sensory properties. Further product development and clinical intervention trials will expand the range of foods that can be made with HAW and provide a deeper understanding of the benefits HAW can provide for improving health and preventing noncommunicable diseases.




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References

  1. AACC International. Method 32-40.01, Resistant Starch in Starch Samples and Plant Materials; Method 32-50.01, Insoluble, Soluble, and Total Dietary Fiber (Codex Definition) by an Enzymatic-Gravimetric Method and Liquid Chromatography. Approved Methods of Analysis, 11th ed. Published online at http://methods.aaccnet.org. AACC International, St. Paul, MN.
  2. AOAC International. Method 2002.02, Resistant Starch Assay procedure; Method 2011.25, Integrated Total Dietary Fiber Assay. Official Methods of Analysis of AOAC International, 19th ed. AOAC International, Rockville, MD, 2012.
  3. Australian Bureau of Statistics. 4364.0.55.012—Australian Health Survey: Consumption of food groups from the Australian Dietary Guidelines, 2011-12. Published online at www.abs.gov.au/ausstats/abs@.nsf/mf/4364.0.55.012. ABS, Belconnen, ACT, Australia, 2012.
  4. Awika, J. M. Major cereal grains production and use around the world. Page 1 in: Advances in Cereal Science: Implications to Food Processing and Health Promotion. Vol. 1089, ACS Symposium Series. J. M. Awika, V. Piironen, and S. Bean eds. American Chemical Society, Washington, DC, 2011.
  5. Bakke, A., Vickers, Z., Marquart, L., and Sjoberg, S. Consumer acceptance of refined and whole wheat breads. Page 255 in: Whole Grains and Health. L. Marquart, D. R. Jacobs, Jr., G. H. McIntosh, K. Poutanen, and M. Reicks, eds. Wiley-Blackwell, Hoboken, NJ, 2007.
  6. Bay State Milling. HealthSense™ high fiber wheat flour. Available online at www.baystatemilling.com/ingredients/high-fiber-wheat-flour. Bay State Milling, Quincy, MA.
  7. Behall, K. M., and Hallfrisch, J. Plasma glucose and insulin reduction after consumption of breads varying in amylose content. Eur. J. Clin. Nutr. 56:913, 2002.
  8. Behall, K. M., Scholfield, D. J., Hallfrisch, J. G., and Liljeberg-Elmstahl, H. G. Consumption of both resistant starch and β-glucan improves postprandial plasma glucose and insulin in women. Diabetes Care 29:976, 2006.
  9. Bertoft, E. Understanding starch structure: Recent progress. Agronomy 7:56, 2017.
  10. Bertoft, E., Piyachomkwan, K., Chatakanonda, P., and Sriroth, K. Internal unit chain composition in amylopectins. Carbohydr. Polym. 74:527, 2008.
  11. Bird, A. R., and Regina, A. High amylose wheat: A platform for delivering human health benefits. J. Cereal Sci. 82:99, 2018.
  12. Blaak, E. E. Carbohydrate quantity and quality and cardio-metabolic risk. Curr. Opin. Clin. Nutr. Metab. Care 19:289, 2016.
  13. Brambila-Macias, J., Shankar, B., Capacci, S., Mazzocchi, M., Perez-Cueto, F. J. A., Verbeke, W., and Traill, W. B. Policy interventions to promote healthy eating: A review of what works, what does not, and what is promising. Food Nutr. Bull. 32:365, 2011.
  14. Butardo, V. M., Anacleto, R., Parween, S., Samso, I., Guzman, K., Alhambra, C. M., Misra, G., and Sreenivasulu, N. Systems genetics identifies a novel regulatory domain of amylose synthesis. Plant Physiol. 173:887, 2017.
  15. Cawley, J. Does anything work to reduce obesity? (Yes, modestly). J. Health Polit. Policy Law 41:463, 2016.
  16. Cho, S. S., Qi, L., Fahey, G. C., and Klurfeld, D. M. Consumption of cereal fiber, mixtures of whole grains and bran, and whole grains and risk reduction in type 2 diabetes, obesity, and cardiovascular disease. Am. J. Clin. Nutr. 98:594, 2013.
  17. Conlon, M. A., Kerr, C. A., McSweeney, C. S., Dunne, R. A., Shaw, J. M., et al. Resistant starches protect against colonic DNA damage and alter microbiota and gene expression in rats fed a Western diet. J. Nutr. 142:832, 2012.
  18. Dalton, S. M. C., Tapsell, L. C., and Probst, Y. Potential health benefits of whole grain wheat components. Nutr. Today 47:63, 2012.
  19. De Moura, F. F., Lewis, K. D., and Falk, M. C. Applying the FDA definition of whole grains to the evidence for cardiovascular disease health claims. J. Nutr. 139:2220S, 2009.
  20. Drewnowski, A., and Popkin, B. M. The nutrition transition: New trends in the global diet. Nutr. Rev. 55:31, 1997.
  21. Fayet-Moore, F., Petocz, P., McConnell, A., Tuck, K., and Mansour, M. The cross-sectional association between consumption of the recommended five food group “Grain (Cereal)”, dietary fibre and anthropometric measures among Australian adults. Nutrients 9:157, 2017.
  22. Gopinath, B., Flood, V. M., Kifley, A., Louie, J. C. Y., and Mitchell, P. Association between carbohydrate nutrition and successful aging over 10 years. J. Gerontol. Ser. A Biol. Sci. Med. Sci. 71:1335, 2016.
  23. Higgins, J. A. Resistant starch and energy balance: Impact on weight loss and maintenance. Crit. Rev. Food Sci. Nutr. 54:1158, 2014.
  24. InterAct Consortium. Dietary fibre and incidence of type 2 diabetes in eight European countries: The EPIC-InterAct Study and a meta-analysis of prospective studies. Diabetologia 58:1394, 2015.
  25. Keenan, M. J., Zhou, J., Hegsted, M., Pelkman, C., Durham, H. A., Coulon, D. B., and Martin, R. J. Role of resistant starch in improving gut health, adiposity, and insulin resistance. Adv. Nutr. 6:198, 2015.
  26. Krebs-Smith, S. M., Guenther, P. M., Subar, A. F., Kirkpatrick, S. I., and Dodd, K. W. Americans do not meet federal dietary recommendations. J. Nutr. 140:1832, 2010.
  27. Lafiandra, D., Riccardi, G., and Shewry, P. R. Improving cereal grain carbohydrates for diet and health. J. Cereal Sci. 59:312, 2014.
  28. Maki, K. C., and Phillips, A. K. Dietary substitutions for refined carbohydrate that show promise for reducing risk of type 2 diabetes in men and women. J. Nutr. 145:159, 2015.
  29. Mann, K. D., Pearce, M. S., McKevith, B., Thielecke, F., and, Seal, C. J. Low whole grain intake in the UK: Results from the National Diet and Nutrition Survey rolling programme 2008-11. Br. J. Nutr. 113:1643, 2015.
  30. McCleary, B. V., DeVries, J. W., Rader, J. I., Cohen, G., Prosky, L., Mugford, D. C., Champ, M., and Okuma, K. Determination of total dietary fiber (CODEX definition) by enzymatic-gravimetric method and liquid chromatography: Collaborative study. J. AOAC Int. 93:221, 2010.
  31. McCleary, B. V., DeVries, J. W., Rader, J. I., Cohen, G., Prosky, L., Mugford, D. C., Champ, M., and Okuma, K. Determination of insoluble, soluble, and total dietary fiber (CODEX definition) by enzymatic-gravimetric method and liquid chromatography: Collaborative study. J. AOAC Int. 95:824, 2012.
  32. Regina, A., Berbezy, P., Kosar-Hashemi, B., Li, S. Z., Cmiel, M., et al. A genetic strategy generating wheat with very high amylose content. Plant Biotechnol. J. 13:1276, 2015.
  33. Regina, A., Bird, A., Topping, D., Bowden, S., Freeman, J., Barsby, T., Kosar-Hashemi, B., Li, Z., Rahman, S., and Morell, M. High-amylose wheat generated by RNA interference improves indices of large-bowel health in rats. Proc. Natl. Acad. Sci. U.S.A. 103:3546, 2006.
  34. Regina, A., Bird, A. R., Li, Z., Rahman, S., Mann, G., Chanliaud, E., Berbezy, P., Topping, D. L., and Morell, M. K. Bioengineering cereal carbohydrates to improve human health. Cereal Foods World 52:182, 2007.
  35. Regina, A., Blazek, J., Gilbert, E., Flanagan, B. M., Gidley, M. J., et al. Differential effects of genetically distinct mechanisms of elevating amylose on barley starch characteristics. Carbohydr. Polym. 89:979, 2012.
  36. Regina, A., Kosar-Hashemi, B., Li, Z., Pedler, A., Mukai, Y., Yamamoto, M., Gale, K., Sharp, P. J., Morell, M. K., and, Rahman, S. Starch branching enzyme IIb in wheat is expressed at low levels in the endosperm compared to other cereals and encoded at a non-syntenic locus. Planta 222:899, 2005.
  37. Robertson, M. D. Dietary-resistant starch and glucose metabolism. Curr. Opin. Clin. Nutr. Metab. Care 15:362, 2012.
  38. Seung, D., Soyk, S., Coiro, M., Maier, B. A., Eicke, S., and Zeeman, S. C. Protein targeting to starch is required for localising granule-bound starch synthase to starch granules and for normal amylose synthesis in Arabidopsis. PLoS Biol. DOI: https://doi.org/10.1371/journal.pbio.1002080. 2015.
  39. Slavin, J. Whole grains and human health. Nutr. Res. Rev. 17:99, 2004.
  40. Vogel, S. Global wheat use for food shows strong growth, while use for seed and ethanol purposes increases marginally. RaboRes. Food Agribus. Published online at https://research.rabobank.com/far/en/sectors/grains-oilseeds/global_wheat_demand_article_2.html. 2017.
  41. Wu, H., Flint, A. J., Qi, Q., van Dam, R. M., Sampson, L. A., Rimm, E. B., Holmes, M. D., Willett, W. C., Hu, F. B., and Sun, Q. Association between dietary whole grain intake and risk of mortality: Two large prospective studies in US men and women. JAMA Intern. Med. 175:373, 2015.